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Analysis of the 3′UTR region of the NOTCH1 gene in chronic lymphocytic leukemia patients

Abramenko, I.V.; Bilous, N.I.; Chumak, A.A.; Dyagil, I.S.; Martina, Z.V. (Experimental Oncology, 2018)

Deregulation of NOTCH1-signalling pathway is common in chronic lymphocytic leukemia (CLL). The most of studies are focused on detection of the hotspot c.7541_7542delCT NOTCH1 mutations in exon 34, while studies of mutations ...
Detection of notch1 c.7544_7545deICT mutation in chronic lymphocytic leukemia using conventional and real-time polymerase chain reaction

Bilous, N.I.; Abramenko, I.V.; Chumak, A.A.; Dyagil, I.S.; Martina, Z.V. (Experimental Oncology, 2016)

Aim: To evaluate real-time polymerase chain reaction (PCR) assay system for detection of NOTCH1 c.7541_754delCT mutation in chronic lymphocytic leukemia (CLL) patients. Material and Methods: A total of 325 CLL patients ...
The distribution of TP53 gene polymorphisms in chronic lymphocytic leukemia patients, sufferers of chornobyl nuclear power plant accident

Bilous, N.I.; Abramenko, I.V.; Chumak, A.A.; Dyagil, I.S.; Martina, Z.M. (Experimental Oncology, 2016)

Previous analyses in a cohort of Chornobyl cleanup workers revealed significantly increased radiation-related risk for all leukemia types, including chronic lymphocytic leukemia (CLL). Numerous investigations emphasized ...
TP53 codon 72 single nucleotide polymorphism in chronic lymphocytic leukemia

Bilous, N.I.; Abramenko, I.V.; Chumak, A.A.; Dyagil, I.S.; Martina, Z.V. (Experimental Oncology, 2014)

Defects in the tumor suppressor gene TP53 are known to be important in chronic lymphocytic leukemia (CLL) and TP53 inactivation is associated with a particularly aggressive form of the disease. The single nucleotide ...

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Перегляд за автором "Bilous, N.I."

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